Pharmacology for Nurses 2nd Edition by Blaine T. Smith, ISBN-13: 978-1284141986

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Pharmacology for Nurses 2nd Edition by Blaine T. Smith, ISBN-13: 978-1284141986

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• Publisher: ‎ Jones & Bartlett Learning; 2nd edition (December 14, 2018)
• Language: ‎ English
• 540 pages
• ISBN-10: ‎ 1284141985
• ISBN-13: ‎ 978-1284141986

Pharmacology for Nurses, Second Edition teaches undergraduate nursing students the basic concepts of pharmacology. The text focuses on critical need-to-know information and draws on the experience of contributing authors in the field of nursing. It takes a new approach to teaching the complex topic of pharmacology through its concise, digestible coverage of material, reader friendly design, and use of images and tables to reinforce content. This text is also intended as a reference for other nursing courses and as part of the nursing professional’s permanent reference library. Pharmacology for Nurses, Second Edition has been written in a manner to reflect real-life clinical applications. The features coverage of the basics of pharmacokinetics and pharmacodynamics as explained in relation to clinical practice. Patient and drug variables as well as drug interactions and effects are also fully explored along with the administration of medications. New to the Second Edition: New case studies and discussion questions Best practices and nursing processes sections found in each chapter Expanded content on the endocrine system featuring coverage of diabetes Revised chapter on cardiovascular medications Updated chapter on the introduction to drug action Navigate 2 Premier Access

Table of Contents:

Cover

Half Title Page

Pharmacology for Nurses

Title Page

Copyright Page

Dedication

Contents

Introduction

About the Editor

Contributors

Reviewers

Chapter 1 Introduction to Pharmacology

Introduction

Nursing and Pharmacology

Drug Classifications

Drug Names

Prescription and Nonprescription Drugs

Controlled Substances

Sources of Drug Information

QSEN Competencies

Overview of the Nursing Process

Assessment

Nursing Diagnosis

Planning

Intervention

Evaluation

Cultural Aspects of Drug Therapy

Legal–Ethical Aspects of Drug Therapy

Medication Errors

How Often Do Medication Errors Occur?

How Can Medication Errors Be Prevented?

Conclusion: Pharmacology in Nursing Practice

Chapter Summary

References

Chapter 2 Introduction to Drug Action: The Interplay of Pharmacodynamics and Pharmacokinetics

Introduction

What Happens After a Drug Is Administered?

Making the Connection: Pharmacology in Clinical Nursing Practice

Pharmacokinetics Versus Pharmacodynamics

The Relationship Between the Drug and the Body

What Is a Drug?

Advances in New Drug Development: Personalized Medicine

Drug Nomenclature

Chemical Name

Generic Name

Brand Name

The Liver: Anatomical First Stop for Orally Administered Drugs

Nursing Considerations

Drug Meet Patient; Patient Meet Drug

Toxicology

Nursing Considerations

What, Then, Is the Right Dose?

The Interplay of Pharmacokinetics and Pharmacodynamics

Pharmacodynamics

Pharmacokinetics

Biopharmaceutics

Nursing Considerations

Clinical Pharmacology

Pharmacodynamics

What the Drug Does to the Body

The Mechanism of Drug Action

The Receptor Molecule

The Nature of Ligand-Receptor Interactions: Chemical Bonding Interactions/Forces

Nursing Considerations

The Drug–Receptor Complex

The Drug–Receptor Interaction and Therapeutic Response

Types of Receptors

Transmembrane Receptor Activation and Response

Signal Transduction

The Dose-Response Relationship

Pharmacodynamic Parameters Obtained from the Dose-Response Curve

Efficacy

Potency

Potency vs. Efficacy: A Source of Confusion

Nursing Considerations

Limitations of a Dose-Response Curve

The Drug Activity Profile

Pharmacodynamic Parameters Obtained from the Drug Activity Profile

Duration of Action

Onset of Action

Therapeutic Index

Classes of Medications

Agonist Drugs

Mimic Ligand-Receptor Activation Responses

Antagonist Drugs

Block the Receptor’s Activation Response

Different Types of Antagonists

Nursing Considerations

Variability in Pharmacodynamics

Pharmacokinetics

How the Body Affects the Drug

Overview of the Pharmacokinetic Processes, ADME

Absorption

Distribution

Metabolism

Elimination

Nursing Considerations

Overview of Pharmacokinetic Terminology

The Pharmacokinetic Parameters Used to Characterize the Rate of Drug Movement

Nursing Considerations

Pharmacokinetic Studies and Determination of Kinetic Parameters

The Plasma Level-Time Curve

Rate Processes of Pharmacokinetics

Zero-Order Rate Process

Nursing Considerations

The First-Order Rate Process

Further Explanation of Rate Constants in Pharmacokinetics

Half-Life in Pharmacokinetics

Nursing Considerations

Drug Absorption: The “A” in ADME

The Pharmacokinetics of Oral Absorption

Bioavailability

Factors Affecting the Rate and Extent of Absorption

Impact of First-Pass Effect on Bioavailability

Steady-State Drug Levels

Nursing Considerations

Distribution: The “D” in ADME

Pharmacokinetics: Rate of Drug Distribution

Pharmacokinetic Models: Compartmental Model Theory

One-Compartment Model

Multicompartment Model

Volume of Distribution

Drug Binding to Plasma Proteins

Competition for Binding Sites

Ramifications of Protein Binding on Therapy

Metabolism: The “M” in ADME

Enzyme Reactions in the Liver

Metabolism and Liver Blood Flow

Drug Interactions Involving Drug Metabolism

Nursing Considerations

Elimination: The “E” in ADME

Biliary Excretion of Drugs

Drug Clearance

Glomerular Filtration

Active Renal Secretion

Tubular Reabsorption

Case Study: Making the Connection to Clinical Nursing

Considerations Affecting Drug Delivery: Dosing Frequency, Timing, and Route

Chronic Medication Use: Long-Term Dosing Regimens

Chapter Summary

References

External Links

CHAPTER 3 Medication Administration

Introduction

Before Administering Medications: The Eight Medication “Rights”

Procedures for Administering Medications

Which Factors Hamper Safe Medication Administration?

Systemic Factors in Medication Errors

Proper Procedure for Administering All Medications

Administering Oral Medications

Injecting Medications Safely

Giving Subcutaneous Injections

Preparing the Medication for a Subcutaneous Injection

Injectable Pens

Rotating Injection Sites for Subcutaneous Injections

General Guidelines for Subcutaneous Injections

Intramuscular Injections

Anatomic Locations for Administering Intramuscular Injections

Supplies Needed for Administering Intramuscular Injections

General Procedure for Administering Intramuscular Injections

Intravenous and Intraosseous Medications

IV Medication Safety Issues

Matters of Key Concern When Administering IV Medications

Administering an IV Medication

Identifying a Site

Inhaled Medications

Proper Procedure for Using a Metered-Dose Inhaler or Dry-Powder Inhaler

Delivering Medication with an Inhaler

Proper Procedure for Administering a Nasal Spray

Using a Nebulizer

Preparing for Nebulizer Therapy

Using the Nebulizer

Medication Transfer Across Permeable Tissues

Administering a Transdermal Patch

Applying Topical Preparations

Vaginal Rings

Administering Vaginal Rings

Administering Rectal Suppositories

Buccal and Sublingual Administration

Administering a Sublingual or Buccal Medication

Medication Errors

What are Medication Administration Errors?

Causes and Prevention of Medication Errors

Conclusion: Medication Administration in Nursing Practice

Chapter Summary

Suggested Readings

References

CHAPTER 4 Central Nervous System Drugs

Nervous System Physiology

Conditions Affecting CNS Function

Drugs Used for Conditions of the Central Nervous System

Classes of Medications for Treating CNS Disorders

Analgesics and Pain Management

Acute Versus Chronic Pain

Narcotics

Nursing Process

Nonsteroidal Anti-Inflammatory Drugs

Nursing Process

Seizure Disorders and Epilepsy

Anticonvulsants

Valproic Acid

Phenobarbital

Levetiracetam

Phenytoin

Benzodiazepines

Anticonvulsant Side Effects

Nursing Process

Neurodegenerative Diseases

Parkinson’s Disease

Carbidopa–Levodopa

Nursing Process for Carbidopa–Levodopa

Ropinirole

Nursing Process for Ropinirole

Benztropine

Nursing Process for Benztropine

Amantadine

Nursing Process for Amantadine

Alzheimer Disease

Nursing Process

Amyotrophic Lateral Sclerosis

Nursing Process

Musculoskeletal Dysfunction

Muscle Relaxants

Specific Drugs and Their Uses

Side Effects and Contraindications

Nursing Process

Local Anesthetics

Specific Drugs and Uses

Nursing Process

Chapter Summary

Suggested Readings

References

CHAPTER 5 Autonomic Nervous System Drugs

Introduction

The Three Systems of the ANS

Anatomy of the Autonomic Nervous System

Integration of ANS Systems

Sympathetic Nervous System

Parasympathetic Nervous System

Neurotransmitters in the Autonomic Nervous System

Adrenergic Receptors

Drugs That Affect the ANS

Adrenergic Agonist Drugs

Nonselective Agents

Selective Adrenergic Agents

Nursing Considerations for Adrenergic Drugs

Adrenergic Antagonists

Alpha-Adrenergic Antagonists

Selectivity

Nursing Considerations for α-Receptor Antagonists

Beta-Adrenergic Antagonists

Selectivity

Nursing Considerations for β-Adrenergic Antagonists

Cholinergic Drugs

Cholinergic Agents

Directly Acting Acetylcholine Receptor Agonist

Acetylcholinesterase Inhibitors

Nursing Considerations for Cholinergic Agonists

Nursing Interventions

Cholinergic Antagonists

Clinical Indications for Use

Individual Cholinergic Antagonists

Nursing Process for Cholinergic Antagonists

Nursing Interventions

Chapter Summary

Suggested Readings

References

CHAPTER 6 Cardiovascular Medications

Introduction

The Cardiovascular System

Treatment of High Blood Pressure

What Is High Blood Pressure?

JNC 7: “Older” Guidelines for Treatment of Hypertension

JNC 8: Updated Guidelines for Treatment of Hypertension

The Renin–Angiotensin–Aldosterone System (RAAS)

Direct Renin Inhibitors

Angiotensin-Converting-Enzyme Inhibitors (ACE Inhibitors)

Angiotensin II Receptor Blockers (ARBs)

Aldosterone Antagonists (AAs)

The Role of the Autonomic Nervous System in Blood Pressure Regulation

Adverse Effects of Beta-Blockers

Blockade of α1-Receptors

Adverse Effects of Alpha-Blockers

Drug–Drug Interactions

Calcium-Channel Blockers

Adverse Effects of Calcium Channel Blockers

Diuretics

Thiazide Diuretics

Loop Diuretics

Potassium-Sparing Diuretics

Hypertensive Emergencies

Cardiac Agents

Coronary Artery Disease

Chest Pain/Angina

Exertional Angina

Variant Angina

Unstable Angina

Antianginal Agents

Nursing Considerations

Hyperlipidemia

Statin Drugs

Fibrates

Niacin

Bile Acid Sequestrants

Congestive Heart Failure

Inotropic Agents

Cardiac Glycosides

Nursing Considerations

Prevention of Thrombosis and Stroke: Anticoagulant Therapy

Anticoagulants

Heparin

Low-Molecular-Weight Heparin

Oral Anticoagulants

Warfarin

Direct Thrombin Inhibitors

Direct Factor Xa Inhibitors

Antiplatelet Agents

Antiarrhythmic Agents

Group I Antiarrhythmics: Sodium-Channel Blockers

Group II Antiarrhythmics: Beta-Blockers

Group III Antiarrhythmics: Potassium-Channel Blockers

Group IV Antiarrhythmics: Calcium-Channel Blockers

Group V Antiarrhythmics: Miscellaneous

Chapter Summary

References

CHAPTER 7 Respiratory Medications

Introduction

Assessment of Lung Function

Asthma

Approach to the Treatment of Asthma

Oral Preventive Medications

Leukotriene-Receptor Antagonists

Thromboxane Antagonists

Oral Corticosteroids

Inhaled Preventive Medications

Inhaled Corticosteroids

Inhaled Long-Acting Beta Agonists

Combination Inhalers (Corticosteroid + LABA)

Injected Preventive Therapies

Monoclonal Antibodies

Methylxanthines

Fast-Acting “Rescue” Medications

Short-Acting Inhaled Beta Agonists

Anticholinergic Agents

Intravenous Corticosteroids

Epinephrine

Late-Phase Asthma Treatment: Emergency Room Only

Chronic Obstructive Pulmonary Disease

COPD Adjunct Therapies

Antibiotics

Smoking Cessation

Mucus Reduction

Smoking-Cessation Therapy

Oral Medications for Smoking Cessation

Antidepressants

Nicotinic-Receptor Agonists

Nicotine Replacement Therapies

Chapter Summary

Suggested Readings

References

CHAPTER 8 Pharmacology of the Gastrointestinal Tract

Introduction

The Nursing Care Process

Drugs to Control Gastric Acidity

Antacids

Drug–Drug Interactions

Histamine 2 (H2) Receptor Antagonists

Drug–Drug Interactions

Proton-Pump Inhibitors

Drug–Drug Interactions

Mucosal Protectants

Drug–Drug Interactions

Drugs to Stimulate Gastrointestinal Motility

Cholinergic Mimetic Agents

Dopamine (D2) Receptor Blockers

Drug–Drug Interactions

Drugs to Control Diarrhea

Opioid Agonists

Drug–Drug Interactions

Bismuth Compounds

Octreotide

Drugs to Relieve Constipation

Bulk-Forming Laxatives

Drug–Drug Interactions

Stimulant Laxatives

Drug–Drug Interactions

Stool Softeners/Surfactants

Drug–Drug Interactions

Osmotic Laxatives

Drug–Drug Interactions

Drugs to Treat Irritable Bowel Syndrome

Anticholinergics

Serotonin 5-HT Receptor Agonists and Antagonists

Drug–Drug Interactions

Chloride-Channel Activators

Drug–Drug Interactions

Drugs to Control Nausea and Vomiting

5-HT3 Receptor Antagonists

Drug–Drug Interactions

Corticosteroids

Neurokinin-1 (NK1) Receptor Antagonists

Drug–Drug Interactions

Dopamine-Receptor Antagonists

Drug–Drug Interactions

Antihistamines and Anticholinergics

Cannabinoids

Drug–Drug Interactions

Drugs to Treat Inflammatory Bowel Disease

Aminosalicylates

Drug–Drug Interactions

Glucocorticoids

Purine Analogs

Drug–Drug Interactions

Methotrexate

Anti-Tumor Necrosis Factor Therapy

Anti-Integrin Therapy

Drug–Drug Interactions

Bile Acid Therapy for Gallstones

Drug–Drug Interactions

Chapter Summary

References

CHAPTER 9 Endocrine System Drugs

Introduction

Endocrine Glands and Their Hormones

Hypothalamus

Pituitary

Pineal Gland

Thyroid

Parathyroid

Thymus

Pancreas

Adrenal Glands

Reproductive Glands

Treating Endocrine Conditions

Diabetes Mellitus

Insulin

Nursing Process

Oral and Injectable Hypoglycemic Medications

Nursing Process

Thyroid Disorders

Thyroid Hormone Replacement

Nursing Process

Thyroid Hormone Suppression

Nursing Process

Polycystic Ovary Syndrome (PCOS)

Nursing Process

Adrenal Disorders

Adrenal Insufficiency

Nursing Process

Hypercortisolism (Cushing Disease)

Nursing Process

Hyperaldosteronism (Conn Disease)

References

CHAPTER 10 Medications for Eye and Ear Disorders

Introduction

Medications for Ophthalmic Disorders

Proper Instillation of Topical Ophthalmic Medication

Drops

Ointments

Glaucoma

Beta Blockers

Therapeutic and Adverse Effects

Drug Interactions

Miotics

Carbonic Anhydrase Inhibitors

Therapeutic and Adverse Effects

Drug Interactions

Alpha-Adrenergic Agonists

Therapeutic and Adverse Effects

Drug Interactions

Prostaglandin Analogs

Therapeutic and Adverse Effects

Adverse Drug Reactions

Chronic Dry or Bloodshot Eyes

Ocular Lubricants

Therapeutic and Adverse Effects

Drug Interactions

Ophthalmic Vasoconstrictors

Therapeutic and Adverse Effects

Drug Interactions

Corticosteroids

Therapeutic and Adverse Effects

Drug Interactions

Ophthalmic Antibiotics

Therapeutic and Adverse Effects

Drug Interactions

Drugs Used in Treating Otic Disorders

Prevention Begins at Birth

Acute Otitis Media

Choosing an Antibacterial Agent

Treatment for Antibiotic-Resistant AOM

Pharmacodynamics

Therapeutic and Adverse Effects

Drug Interactions

Otitis Media with Effusion

Otitis Externa and Its Management

Prevention

Treatment

Topical Medications

Systemic Treatment

Fungal Otitis Externa (Otomycosis)

Treatment

Analgesics

Chapter Summary

References

CHAPTER 11 Pharmacology of the Genitourinary System

Introduction

Urinary Tract Infections

Complicated UTI in Adults

Complicated UTI in Pediatric Patients

Medications for Treatment of Uncomplicated UTI (Cystitis)

Trimethoprim-Sulfamethoxazole

Nitrofurantoin

Fosfomycin Trometamol

Second-Line Agents for UTI

Beta-Lactam Agents

Non-Antimicrobial Biological Mediators for Prevention of Uncomplicated Recurrent Cystitis

Cranberry Juice, Capsules, or Tablets

Topical/Local Estrogen

Vaccines and Probiotic Application

Treatment of Complicated UTI

Candida albicans Vaginitis (Vaginal Yeast Infection)

Benign Hyperplasia of the Prostate

Medications for the Treatment of BPH

Antimuscarinic Agents (Tolterodine)

Selective α1-Adrenoreceptor Antagonists (Alfuzosin, Prazosin, Doxazosin, Tamsulosin, Terazosin)

5-α-Reductase Inhibitors (Finasteride, Dutasteride)

PDE-5 Inhibitors (Tadalafil)

Erectile Dysfunction

Medications for the Treatment of ED

PDE-5 Inhibitors (Sildenafil, Tadalafil, Vardenafil)

Alprostadil

Sexually Transmitted Infections

Sexually Transmitted Viral Infections

HPV, Genital Warts, and Cervical Cancer

Herpes and HIV Infections

Sexually Transmitted Bacterial Infections

Sexually Transmitted Parasitic Infections

Female Hormonal Contraception

Estrogen Analogs

Progestins

Testosterone

Pharmacodynamics

Delivery System Comparison

Oral Hormonal Contraceptives

Transdermal Contraceptive System

Vaginal Rings

Implants

Intrauterine Device

Emergency Contraception

Urinary Incontinence

Chapter Summary

References

CHAPTER 12 Drugs Associated with Pregnancy, Labor and Delivery, and Lactation

Introduction

FDA Pregnancy Categories

Medication Use on a Preconception Basis and in Early Pregnancy

Physiological Changes in Pregnancy

Use of Nonprescribed and Illicit Drugs

Patient Emotions Around Medication Use

Common Conditions Arising in Pregnancy

Constipation

Diabetes Mellitus

Heartburn

Nausea and Vomiting in Pregnancy

Hypertension in Pregnancy

Group B Streptococcal Infection

Human Immunodeficiency Virus

Neoplastic Disease

Drugs Used During Labor

Preterm Labor

Tocolytic Medications

Labor Induction

Analgesia/Anesthesia

Drugs Used During the Postpartum Period

Drugs Administered During Lactation

Chapter Summary

References

CHAPTER 13 Pharmacology in Dermatologic Conditions

Introduction

Topical Administration

Systemic Administration

Intralesional Administration

Physiological Factors Affecting Transdermal Medication Administration

Acne Medications: An Example of Delivery Systems

Pharmacology of Topical Acne Medication

Benzoyl Peroxide

Salicylic Acid

Tretinoin

Pharmacology of Systemic Acne Medications

Tetracyclines

Isotretinoin

Hormonal Medications

Pharmacology of Intralesional Injection Acne Treatment

Intralesional Steroid Injection

Atopic Dermatitis

Pharmacology of Topical Preparations for AD

Triamcinolone Acetonide

Emollient Ointment

Bacterial Skin Infections

Antifungal Preparations

Pharmacology of Common Antifungal Medications

Ketoconazole 2% Cream

Terbinafine

Chapter Summary

References

CHAPTER 14 Pharmacology of Psychotropic Medications

Introduction

Delusional Disorders (Psychoses): Schizophrenia and Antipsychotic Medications

Antipsychotic Medications

First-Generation Antipsychotics (FGAs)

Second-Generation Antipsychotics

Depression and Anxiety

Monoamine Oxidase Inhibitors

Adverse Reactions

Drug–Drug Interactions

Prescribing Considerations

Tricyclic Antidepressants (TCAs)

Adverse Reactions

Drug–Drug Interactions

Prescribing Considerations

SSRIs and SNRIs

Adverse Reactions

Drug–Drug Interactions

Prescribing Considerations

Buspirone

Adverse Reactions

Drug–Drug Interactions

Benzodiazepines

Adverse Reactions

Drug–Drug Interactions

Prescribing Considerations

Bipolar Disorder

Mood Stabilizers

First-Line Medications: Lithium, Valproic Acid, and Carbamazepine

Lamotrigine

Antipsychotic Drugs in Bipolar Disorder

Prescribing Considerations for Drugs Used To Treat Bipolar Disorder

Attention-Deficit Disorder and Attention-Deficit/Hyperactivity Disorder

Stimulant Medications

Adverse Effects

Drug–Drug Interactions

Nonstimulant Medications

Adverse Reactions

Drug–Drug Interactions

Prescribing Considerations for Drugs Used for ADD/ADHD

Sleep Disorders

Sleep Hypnotic Drugs

Adverse Reactions

Drug–Drug Interactions

Other Sleep Aids

Prescribing Considerations for Sleep Aids

Chapter Summary

References

CHAPTER 15 Pharmacology of Anesthetic Drugs

Introduction

Types of Anesthesia

Local and Topical Anesthesia

Adverse Effects

Inhalational Anesthesia

Drugs Used for Inhalational Anesthesia

Nitrous Oxide

Isoflurane

Desflurane

Sevoflurane

Intravenous Anesthetics

Induction Anesthetics

Propofol

Ketamine

Etomidate

Barbiturates

Anesthetic Adjuncts

Benzodiazepines

Opioids

Nonanesthetic Adjuncts

Muscle Relaxants

Acetylcholinesterase Inhibitors

Anticholinergic Drugs

Antiemetics

Chapter Summary

References

CHAPTER 16 Pharmacology of Antimicrobial Drugs

Introduction

Antibacterials

Sulfonamides

Drug Interactions and Contraindications

Nursing Considerations

Tetracyclines

Nursing Considerations

β–Lactam Antibiotics

Mechanism of Action

Penicillins

Drug Interactions and Contraindications

Nursing Implications

Cephalosporins

Drug Interactions and Contraindications

Nursing Implications

Carbapenems

Drug Interactions and Contraindications

Nursing Considerations

Monobactams

Drug Interactions and Contraindications

Nursing Considerations

Beta-Lactamase Inhibitors

Drug Interactions and Contraindications

Aminoglycosides

Drug Interactions and Contraindications

Nursing Considerations

Macrolides

Drug Interactions and Contraindications

Nursing Considerations

Quinolones and Fluoroquinolones

Drug Interactions and Contraindications

Nursing Considerations

Lincosamides

Drug Interactions and Contraindications

Nursing Considerations

Vancomycin

Drug Interactions and Contraindications

Nursing Considerations

Newer Anti-Infective Drugs for Resistant Infections

Drug Interactions and Contraindications

Quinupristin/Dalfopristin

Linezolid

Nursing Considerations

Quinupristin/Dalfopristin

Linezolid

Antitubercular Drugs

Drug Interactions and Contraindications

Isoniazid (INH)

Ethambutol

Ethionamide

Pyrazinamide (PZA)

Rifampin

Streptomycin

Nursing Considerations

Isoniazid

Ethambutol

Ethionamide

Pyrazinamide

Rifampin

Streptomycin

Antifungal Agents

Drug Interactions and Contraindications

Nursing Considerations

Antiparasitic Agents

Protozoal Infections

Antiprotozoal Medications

Drug Interactions and Contraindications

Nursing Considerations

Anthelmintic Agents

Drug Interactions and Contraindications

Nursing Considerations

Antivirals

Anti-Herpesvirus Agents

Anti-Influenza Agents

Anti-Hepatitis Agents

Antiretroviral Agents

Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

Drug Interactions and Contraindications

Nursing Considerations

Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)

Drug Interactions and Contraindications

Nursing Considerations

Protease Inhibitors (PIs)

Drug Interactions and Contraindications

Nursing Considerations

Entry Inhibitors (EI)

Integrase Strand Transfer Inhibitors (ISTIs)

Chapter Summary

References

Glossary

Index

Blaine Templar Smith, R.Ph., Ph.D. earned Bachelor’s degrees in Chemistry and Pharmacy, and a Ph.D. in Pharmaceutical Sciences (with emphasis in Nuclear Pharmacy and Immunology) at the University of Oklahoma. Dr. Smith is a Registered Pharmacist in both Oklahoma and Massachusetts, practicing in a very wide spectrum of settings, including hospital in-patient, long-term care centers, independent and chain retail pharmacies, and Indian Health Service clinics and hospitals. He completed a Post-Doctoral fellowship at the University of Oklahoma Genome Sequencing Center, participating in the Human Genome Project. Dr. Smith has been a faculty member at the University of Oklahoma College of Pharmacy, the Massachusetts College of Pharmacy and Health Sciences-Worcester, faculty member and Chair of the Department of Pharmaceutical Sciences at the Saint Joseph University School of Pharmacy, and Visiting Fellow at the University of Massachusetts Medical School. He has written, edited, and published several reference and textbooks related to the fields of medicine, pharmacy, and nursing. Additionally, he provides online teaching (both live and asynchronous) and continuing education, for participants ranging from ten-year-old Gifted and Talented students from around the globe, to health care professionals with continuing education licensure requirements.

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